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Anti-IGF2/IGF-II Antibody (6S876)

😃Good
Catalog No. TMAH-00600
Alias Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2

Anti-IGF2/IGF-II Antibody (6S876) is an antibody targeting IGF2/IGF-II. Anti-IGF2/IGF-II Antibody (6S876) can be used in ELISA.

Anti-IGF2/IGF-II Antibody (6S876)

Anti-IGF2/IGF-II Antibody (6S876)

😃Good
Catalog No. TMAH-00600Alias Somatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2
Anti-IGF2/IGF-II Antibody (6S876) is an antibody targeting IGF2/IGF-II. Anti-IGF2/IGF-II Antibody (6S876) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$208 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA

Reactivity: Human
AliasSomatomedin-A, Somatomedin A, PP1446, IGF-II, IGF2
Ig Type
Rabbit IgG
Clone
6S876
Reactivity
Human
Application
ELISA
Antibody Type
Monoclonal
Subcellular LocalizationSecreted.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human IGF2
Antigen Species
Human
Gene ID
3481
Uniprot ID
Biology Area
Signal Transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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