BAX Protein, Human, Recombinant (GST)

Name: BAX Protein, Human, Recombinant (GST)
Brand: TargetMol
SKU: TMPC-00095
Rating: 4.5 (1 reviews)

(Synonyms: Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, BAX, Apoptosis regulator BAX) Copy Product Info

Synonyms: Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, BAX, Apoptosis regulator BAX

Catalog No. TMPC-00095 Copy Product Info

BAX Protein, Human, Recombinant (GST) is expressed in E. coli. The accession number is Q07812.

Pack Size	Price	USA Stock	Global Stock	Quantity
20 µg	$953	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
Description	BAX Protein, Human, Recombinant (GST) is expressed in E. coli. The accession number is Q07812.
Species	Human
Expression System	E. coli
Tag	N-GST
Accession Number	Q07812
Construction	Recombinant full length human BAX was expressed in E. coli cells using an N-terminal GST tag.
Protein Purity	>70% as determined by SDS-PAGE.
Formulation	Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Synonyms	Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, BAX, Apoptosis regulator BAX
Research Background	BCL2 associated X (BAX) is traditionally thought to be regulated by anti-apoptotic BCL-2 family members. BCL-2-associated X protein (BAX) is a critical apoptotic regulator that can be transformed from a cytosolic monomer into a lethal mitochondrial oligomer, The pro-apoptotic BCL-2 protein BAX commits human cells to apoptosis by permeabilizing the outer mitochondrial membrane. BAX activation has been suggested to require the separation of helix alpha5 from alpha6 - the 'latch' from the 'core' domain - among other conformational changes. BCL-2-associated X (BAX) protein acts as a gatekeeper in regulating mitochondria-dependent apoptosis. Under cellular stress, BAX becomes activated and transforms into a lethal oligomer that causes mitochondrial outer membrane permeabilization (MOMP).

Chemical Properties

Molecular Weight

~49 kDa

Storage & Solubility Information

Shipping	Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

You can also refer to dose conversion for different animals. More Dose Conversion

Related Tags: BAX Protein, Human, Recombinant (GST) chemical structure | BAX Protein, Human, Recombinant (GST) molecular weight