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Anti-Smad5 Antibody (4P191)
🥰Excellent
Catalog No. TMAB-12943
Antibody Type: Recombinant Rabbit Monoclonal
Application: IHC-P,IHC-Fr,IF
Reactivity: Human,Mouse (predicted:Rat)
Anti-Smad5 Antibody (4P191)
Anti-Smad5 Antibody (4P191)
🥰Excellent
Catalog No. TMAB-12943
Antibody Type: Recombinant Rabbit Monoclonal
Application: IHC-P,IHC-Fr,IF
Reactivity: Human,Mouse (predicted:Rat)
Application: IHC-P,IHC-Fr,IF
Reactivity: Human,Mouse (predicted:Rat)
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Smad5 Antibody (4P191) is a Rabbit antibody targeting Smad5. Anti-Smad5 Antibody (4P191) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 4P191 |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. |
| Tissue Specificity | Ubiquitous. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Immunogen | A synthesized peptide: human SMAD5 |
| Antigen Species | Human |
| Gene Name | SMAD5 |
| Gene ID | |
| Protein Name | Mothers against decapentaplegic homolog 5 |
| Uniprot ID | |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). |
| Molecular Weight | Theoretical: 51 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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