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Anti-DOCK2 Antibody (7U659)
😃Good
Catalog No. TMAB-05272
Anti-DOCK2 Antibody (7U659) is a Rabbit antibody targeting DOCK2. Anti-DOCK2 Antibody (7U659) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-DOCK2 Antibody (7U659)
Anti-DOCK2 Antibody (7U659)
😃Good
Catalog No. TMAB-05272
Anti-DOCK2 Antibody (7U659) is a Rabbit antibody targeting DOCK2. Anti-DOCK2 Antibody (7U659) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DOCK2 Antibody (7U659) is a Rabbit antibody targeting DOCK2. Anti-DOCK2 Antibody (7U659) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 7U659 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Intracytoplasmic membrane. Peripheral membrane protein. Note=Colocalizes with F-actin. |
| Tissue Specificity | Specifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
| Immunogen | A synthesized peptide: human Dedicator of cytokinesis protein 2 |
| Antigen Species | Human |
| Gene Name | DOCK2 |
| Gene ID | |
| Protein Name | Dedicator of cytokinesis protein 2 |
| Uniprot ID | |
| Function | DOCK2 (dedicator of cytokinesis 2) is a hematopoietic cell-specific protein that participates in the cytoskeletal rearrangements required for lymphocyte migration in response to chemokines. DOCK2 activates the small GTPases RAC1 and RAC2 and may also be involved in IL2 transcriptional activation via the activation of RAC2. |
| Molecular Weight | Theoretical: 212 kDa. Actual: 212 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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