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Anti-Thrombomodulin Antibody (2C528) is an antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (2C528) can be used in ELISA,IHC.
| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $349 | 7-10 days | 
| Description | Anti-Thrombomodulin Antibody (2C528) is an antibody targeting Thrombomodulin. Anti-Thrombomodulin Antibody (2C528) can be used in ELISA,IHC. | 
| Synonyms | TM, thrombomodulin, THRM, THPH12, CD141, BDCA3, AHUS6 | 
| Ig Type | Rabbit IgG | 
| Clone | 2C528 | 
| Reactivity | Human | 
| Verified Activity | IHC image of TMAH-01168 diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. | 
| Application | |
| Recommended Dose | IHC:1:50-1:200. | 
| Antibody Type | Monoclonal | 
| Subcellular Localization | Membrane; Single-pass type I membrane protein. | 
| Tissue Specificity | Endothelial cells are unique in synthesizing thrombomodulin. | 
| Construction | Recombinant Antibody | 
| Purification | Affinity-chromatography | 
| Appearance | Liquid | 
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | 
| Research Background | Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. | 
| Conjucates | Unconjugated | 
| Immunogen | A synthetic peptide: Human THBD | 
| Antigen Species | Human | 
| Gene Name | THBD | 
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cardiovascular, Stem cells | 
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. | 
| Transport | Shipping with blue ice. | 

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