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Anti-KDM4B Antibody (3X256)

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Catalog No. TMAB-07976

Anti-KDM4B Antibody (3X256) is a Rabbit antibody targeting KDM4B. Anti-KDM4B Antibody (3X256) can be used in WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF.

Anti-KDM4B Antibody (3X256)

Anti-KDM4B Antibody (3X256)

😃Good
Catalog No. TMAB-07976
Anti-KDM4B Antibody (3X256) is a Rabbit antibody targeting KDM4B. Anti-KDM4B Antibody (3X256) can be used in WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KDM4B Antibody (3X256) is a Rabbit antibody targeting KDM4B. Anti-KDM4B Antibody (3X256) can be used in WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
3X256
Reactivity
Human,Mouse,Rat
Application
WB
ICC/IF
FCM
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Chromosome. Associates with euchromatic regions. Does not associate with heterochromatin.
Tissue SpecificityExpressed in all tissues examined, with high levels in fetal liver, thymus, lymph node, spleen and peripheral blood leukocytes and lower level in bone marrow.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundEnables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer. [provided by Alliance of Genome Resources, Apr 2022]
Antigen Details
Gene Name
KDM4B
Gene ID
23030
Protein Name
Lysine-specific demethylase 4B
Function
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Chemical Properties
Molecular WeightTheoretical: 122 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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