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Anti-PRKRA Antibody (9V632)

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Catalog No. TMAB-11747 Copy Product Info
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Anti-PRKRA Antibody (9V632) is a Rabbit antibody targeting PRKRA. Anti-PRKRA Antibody (9V632) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Anti-PRKRA Antibody
(9V632)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PRKRA Antibody (9V632) is a Rabbit antibody targeting PRKRA. Anti-PRKRA Antibody (9V632) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
9V632
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
FCM=1:50-100; IF=1:100-200; IHC-Fr=1:100-200; IHC-P=1:100-200; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm > perinuclear region.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundActivates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing.
Antigen Details
Immunogen
A synthesized peptide: human PRKRA
Antigen Species
Human
Gene Name
PRKRA
Gene ID
Protein Name
Interferon-inducible double-stranded RNA-dependent protein kinase activator A
Uniprot ID
Function
Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.
Chemical Properties
Molecular WeightTheoretical: 34 kDa. Actual: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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