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Anti-PRKRA Antibody (9V632) is a Rabbit antibody targeting PRKRA. Anti-PRKRA Antibody (9V632) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
| Description | Anti-PRKRA Antibody (9V632) is a Rabbit antibody targeting PRKRA. Anti-PRKRA Antibody (9V632) can be used in FCM, IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 9V632 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1:50-100; IF=1:100-200; IHC-Fr=1:100-200; IHC-P=1:100-200; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm > perinuclear region. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. |
| Immunogen | A synthesized peptide: human PRKRA |
| Antigen Species | Human |
| Gene Name | PRKRA |
| Gene ID | |
| Protein Name | Interferon-inducible double-stranded RNA-dependent protein kinase activator A |
| Uniprot ID | |
| Function | Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. |
| Molecular Weight | Theoretical: 34 kDa. Actual: 34 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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