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Anti-KDM1B Antibody (8C367)
😃Good
Catalog No. TMAB-07975
Anti-KDM1B Antibody (8C367) is a Rabbit antibody targeting KDM1B. Anti-KDM1B Antibody (8C367) can be used in WB,IP.
Anti-KDM1B Antibody (8C367)
Anti-KDM1B Antibody (8C367)
😃Good
Catalog No. TMAB-07975
Anti-KDM1B Antibody (8C367) is a Rabbit antibody targeting KDM1B. Anti-KDM1B Antibody (8C367) can be used in WB,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-KDM1B Antibody (8C367) is a Rabbit antibody targeting KDM1B. Anti-KDM1B Antibody (8C367) can be used in WB,IP. |
| Ig Type | IgG |
| Clone | 8C367 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. |
| Immunogen | A synthesized peptide: human KDM1B |
| Antigen Species | Human |
| Gene Name | KDM1B |
| Gene ID | |
| Protein Name | Lysine-specific histone demethylase 1B |
| Uniprot ID | |
| Function | Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. |
| Molecular Weight | Theoretical: 92 kDa. Actual: 92 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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