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Anti-FGF1 Antibody (2H590)

😃Good
Catalog No. TMAB-05982

Anti-FGF1 Antibody (2H590) is a Rabbit antibody targeting FGF1. Anti-FGF1 Antibody (2H590) can be used in WB.

Anti-FGF1 Antibody (2H590)

Anti-FGF1 Antibody (2H590)

😃Good
Catalog No. TMAB-05982
Anti-FGF1 Antibody (2H590) is a Rabbit antibody targeting FGF1. Anti-FGF1 Antibody (2H590) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FGF1 Antibody (2H590) is a Rabbit antibody targeting FGF1. Anti-FGF1 Antibody (2H590) can be used in WB.
Ig Type
IgG
Clone
2H590
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59.
Tissue SpecificityPredominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPlays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as a potent mitogen in vitro.
Antigen Details
Immunogen
A synthesized peptide: human FGF1
Antigen Species
Human
Gene Name
FGF1
Gene ID
Protein Name
Fibroblast growth factor 1
Uniprot ID
Function
The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.
Chemical Properties
Molecular WeightTheoretical: 17 kDa. Actual: 17 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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