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Anti-Thioredoxin Antibody (4M231)
Catalog No. TMAB-13510 Copy Product Info
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Anti-Thioredoxin Antibody (4M231) is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Antibody (4M231) can be used in WB,FCM.
Anti-Thioredoxin Antibody (4M231)
Copy Product Info🥰Excellent
Catalog No. TMAB-13510
Anti-Thioredoxin Antibody (4M231) is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Antibody (4M231) can be used in WB,FCM.
Anti-Thioredoxin Antibody
(4M231)
(4M231)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Thioredoxin Antibody (4M231) is a Rabbit antibody targeting Thioredoxin. Anti-Thioredoxin Antibody (4M231) can be used in WB,FCM. |
| Ig Type | IgG |
| Clone | 4M231 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with Thioredoxin monoclonal antibody, unconjugated (TMAB-13510) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Secreted. Note=Secreted by a leaderless secretory pathway. Predominantly in the cytoplasm in non irradiated cells. Radiation induces translocation of TRX from the cytoplasm to the nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. |
| Immunogen | A synthesized peptide: human Thioredoxin |
| Antigen Species | Human |
| Gene Name | TXN |
| Gene ID | |
| Protein Name | Thioredoxin |
| Uniprot ID | |
| Function | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |
| Molecular Weight | Theoretical: 12 kDa. Actual: 12 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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