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Anti-KIF4A Antibody (8C211)

😃Good
Catalog No. TMAB-08049

Anti-KIF4A Antibody (8C211) is a Rabbit antibody targeting KIF4A. Anti-KIF4A Antibody (8C211) can be used in WB,FCM,ICC/IF.

Anti-KIF4A Antibody (8C211)

Anti-KIF4A Antibody (8C211)

😃Good
Catalog No. TMAB-08049
Anti-KIF4A Antibody (8C211) is a Rabbit antibody targeting KIF4A. Anti-KIF4A Antibody (8C211) can be used in WB,FCM,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KIF4A Antibody (8C211) is a Rabbit antibody targeting KIF4A. Anti-KIF4A Antibody (8C211) can be used in WB,FCM,ICC/IF.
Ig Type
IgG
Clone
8C211
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-2000; FCM: 1:50-100; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus matrix. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Note=Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis.
Tissue SpecificityHighly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundIron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis. Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis.
Antigen Details
Immunogen
A synthesized peptide: human Chromokinesin A
Antigen Species
Human
Gene Name
KIF4A
Gene ID
Protein Name
Chromosome-associated kinesin KIF4A
Uniprot ID
Function
Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
Chemical Properties
Molecular WeightTheoretical: 140 kDa. Actual: 150 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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