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Anti-IGF2R/M6PR Antibody (1F622)
Catalog No. TMAB-07548 Copy Product Info
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Anti-IGF2R/M6PR Antibody (1F622) is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Antibody (1F622) can be used in WB.
Anti-IGF2R/M6PR Antibody (1F622)
Copy Product Info🥰Excellent
Catalog No. TMAB-07548
Anti-IGF2R/M6PR Antibody (1F622) is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Antibody (1F622) can be used in WB.
Anti-IGF2R/M6PR Antibody
(1F622)
(1F622)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IGF2R/M6PR Antibody (1F622) is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Antibody (1F622) can be used in WB. |
| Ig Type | IgG |
| Clone | 1F622 |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Sample: Lane 1: Human HeLa cell lysates Lane 2: Human Jurkat cell lysates Primary: Anti-IGF2R/M6PR (TMAB-07548) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 300 kDa Observed band size: 300 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS, Glycerol, BSA. |
| Concentration | 1mg/ml |
| Research Background | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
| Immunogen | KLH conjugated synthetic peptide: human IGF2R |
| Antigen Species | Human |
| Gene Name | IGF2R |
| Gene ID | |
| Protein Name | Cation-independent mannose-6-phosphate receptor |
| Uniprot ID | |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
| Molecular Weight | Theoretical: 300 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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