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Anti-NR3C1 Antibody (1M615) (Synonyms: nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)...)

Catalog No. TMAC-01671 Copy Product Info
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Anti-NR3C1 Antibody (1M615) is a Rabbit antibody targeting NR3C1. Anti-NR3C1 Antibody (1M615) can be used in FCM,WB.

Anti-NR3C1 Antibody (1M615)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01671
Synonyms nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), GRL, GR, GCRST, GCR, GCCR

Anti-NR3C1 Antibody (1M615) is a Rabbit antibody targeting NR3C1. Anti-NR3C1 Antibody (1M615) can be used in FCM,WB.

Anti-NR3C1 Antibody
(1M615)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NR3C1 Antibody (1M615) is a Rabbit antibody targeting NR3C1. Anti-NR3C1 Antibody (1M615) can be used in FCM,WB.
Synonymsnuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), GRL, GR, GCRST, GCR, GCCR
Ig Type
IgG
Clone
1M615
Reactivity
Human,Mouse,Rat,zebrafish
Verified Activity
1. Western blot analysis of Glucocorticoid Receptor on different lysates using anti-Glucocorticoid Receptor antibody at 1/1,000 dilution. Positive control: Lane 1: zebrafish, Lane 2: A549, Lane 3: HepG2.
2. Western blot analysis of Glucocorticoid Receptor on hybrid fish (crucian-carp) heart tissue lysate using anti-Glucocorticoid Receptor antibody at 1/500 dilution.
3. Flow cytometric analysis of NIH/3T3 cells with Glucocorticoid Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-5000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR α. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 86 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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