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Anti-IRF7 Antibody (8B964)
😃Good
Catalog No. TMAC-02228
Alias IRF7H, IRF7A, IRF-7, IRF7, IRF 7H, IRF 7A, Interferon regulatory factor 7H, Interferon regulatory factor 7
Anti-IRF7 Antibody (8B964) is a Rabbit antibody targeting IRF7. Anti-IRF7 Antibody (8B964) can be used in WB,ICC/IF,IHC,IP,FCM.
Anti-IRF7 Antibody (8B964)
Anti-IRF7 Antibody (8B964)
😃Good
Catalog No. TMAC-02228Alias IRF7H, IRF7A, IRF-7, IRF7, IRF 7H, IRF 7A, Interferon regulatory factor 7H, Interferon regulatory factor 7
Anti-IRF7 Antibody (8B964) is a Rabbit antibody targeting IRF7. Anti-IRF7 Antibody (8B964) can be used in WB,ICC/IF,IHC,IP,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-IRF7 Antibody (8B964) is a Rabbit antibody targeting IRF7. Anti-IRF7 Antibody (8B964) can be used in WB,ICC/IF,IHC,IP,FCM. |
| Synonyms | IRF7H, IRF7A, IRF-7, IRF7, IRF 7H, IRF 7A, Interferon regulatory factor 7H, Interferon regulatory factor 7 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat,zebrafish |
| Verified Activity | 1. Western blot analysis of IRF7 on different lysates using anti-IRF7 antibody at 1/1,000 dilution. Positive control: Lane 1: Jurkat, Lane 2: Raji. 2. Western blot analysis of IRF7 on hybrid fish (crucian-carp) brain tissue lysate using anti-IRF7 antibody at 1/500 dilution. 3. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-IRF7 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IRF7 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IRF7 antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IRF7 antibody. Counter stained with hematoxylin. 7. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-IRF7 antibody. Counter stained with hematoxylin. 8. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-IRF7 antibody. Counter stained with hematoxylin. 9. ICC staining IRF7 in PC-12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 10. ICC staining IRF7 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 11. ICC staining IRF7 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 12. Flow cytometric analysis of Jurkat cells with IRF7 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7 and IFN consensus sequence-binding protein (ICSBP). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 54 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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