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Anti-Caveolin-2 Antibody (6X266)
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Catalog No. TMAB-03705
Anti-Caveolin-2 Antibody (6X266) is a Rabbit antibody targeting Caveolin-2. Anti-Caveolin-2 Antibody (6X266) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.
Anti-Caveolin-2 Antibody (6X266)
Anti-Caveolin-2 Antibody (6X266)
😃Good
Catalog No. TMAB-03705
Anti-Caveolin-2 Antibody (6X266) is a Rabbit antibody targeting Caveolin-2. Anti-Caveolin-2 Antibody (6X266) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Caveolin-2 Antibody (6X266) is a Rabbit antibody targeting Caveolin-2. Anti-Caveolin-2 Antibody (6X266) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP. |
| Ig Type | IgG |
| Clone | 6X266 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Golgi apparatusmembrane; Peripheral membrane protein. Cell membrane; Peripheralmembrane protein. Membrane, caveola; Peripheral membrane protein.Note=Potential hairpin-like structure in the membrane. Membraneprotein of caveolae. Tyr-19-phosphorylated form is enriched atsites of cell-cell contact and is translocated to the nucleus incomplex with MAPK1 in response to insulin (By similarity).Tyr-27-phosphorylated form is located both in the cytoplasm andplasma membrane. CAV1-mediated Ser-23-phosphorylated form locatesto the plasma membrane. Ser-36-phosphorylated form resides inintracellular compartments. |
| Tissue Specificity | Expressed in endothelial cells, smooth musclecells, skeletal myoblasts and fibroblasts. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. |
| Immunogen | A synthesized peptide: human Caveolin 2 |
| Antigen Species | Human |
| Gene Name | CAV2 |
| Gene ID | |
| Protein Name | Caveolin-2 |
| Uniprot ID | |
| Function | May act as a scaffolding protein within caveolarmembranes. Interacts directly with G-protein alpha subunits and canfunctionally regulate their activity. Acts as an accessory proteinin conjunction with CAV1 in targeting to lipid rafts and drivingcaveolae formation. The Ser-36 phosphorylated form has a role inmodulating mitosis in endothelial cells. Positive regulator ofcellular mitogenesis of the MAPK signaling pathway. Required forthe insulin-stimulated nuclear translocation and activation ofMAPK1 and STAT3, and the subsequent regulation of cell cycleprogression (By similarity). |
| Molecular Weight | Theoretical: 18 kDa. Actual: 18 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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