Anti-Caveolin-2 Antibody (6X266) is a Rabbit antibody targeting Caveolin-2. Anti-Caveolin-2 Antibody (6X266) can be used in ICC/IF, IP, WB.

IgG

6X266

Human

1. 4% Paraformaldehyde-fixed Hela (H) cell; Triton X-100 at r. T. for 20 min; Antibody incubation with (Caveolin-2) monoclonal Antibody, unconjugated (TMAB-03705) 1: 100, 90 min at 37°C; followed by conjugated Goat Anti-Rabbit IgG antibody (green, BF488) at 37°C for 90 min, DAPI (blue) was used to stain the cell nuclei. PBS instead of the primary antibody was used as the blank control.
2. 25 ug total protein per lane of various lysates (see on figure) probed with Caveolin-2 monoclonal antibody, unconjugated (TMAB-03705) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.

ICC/IF=1:50-200; IP=1:20-50; WB=1:500-2000

Monoclonal

A synthesized peptide: human Caveolin 2

Human

CAV2

Caveolin-2

May act as a scaffolding protein within caveolarmembranes. Interacts directly with G-protein alpha subunits and canfunctionally regulate their activity. Acts as an accessory proteinin conjunction with CAV1 in targeting to lipid rafts and drivingcaveolae formation. The Ser-36 phosphorylated form has a role inmodulating mitosis in endothelial cells. Positive regulator ofcellular mitogenesis of the MAPK signaling pathway. Required forthe insulin-stimulated nuclear translocation and activation ofMAPK1 and STAT3, and the subsequent regulation of cell cycleprogression (By similarity).