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Anti-GUCY2C Antibody (7S256)

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Catalog No. TMAH-00524
Alias STAR, STA receptor, MUCIL, GUCY2C, GUC2CEC 4.6.1.2, GUC2C, Guanylyl cyclase C, GC-C, GCC, EC 4.6.1, DIAR6

Anti-GUCY2C Antibody (7S256) is an antibody targeting GUCY2C. Anti-GUCY2C Antibody (7S256) can be used in ELISA, FCM.

Anti-GUCY2C Antibody (7S256)

Anti-GUCY2C Antibody (7S256)

😃Good
Catalog No. TMAH-00524Alias STAR, STA receptor, MUCIL, GUCY2C, GUC2CEC 4.6.1.2, GUC2C, Guanylyl cyclase C, GC-C, GCC, EC 4.6.1, DIAR6
Anti-GUCY2C Antibody (7S256) is an antibody targeting GUCY2C. Anti-GUCY2C Antibody (7S256) can be used in ELISA, FCM.
Pack SizePriceAvailabilityQuantity
50 μL$209 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Mouse Monoclonal

Application: ELISA, FCM

Reactivity: Human
AliasSTAR, STA receptor, MUCIL, GUCY2C, GUC2CEC 4.6.1.2, GUC2C, Guanylyl cyclase C, GC-C, GCC, EC 4.6.1, DIAR6
Ig Type
Mouse IgG2a
Clone
7S256
Reactivity
Human
Verified Activity
1. The Binding Activity of Huamn GUCY2C with Anti-GUCY2C recombinant Antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized human GUCY2C at 5 μg/mL can bind Anti-GUCY2C recombinant antibody, the EC50 is 3.049-4.660 ng/mL.
2. T84 cells were stained with Mouse IgG2a (green line) and anti-GUCY2C antibody (red line) (2µg/1*10^6 cells), washed and then followed by FITC-conjugated Goat Anti-Mouse IgG(H+L) antibody and analyzed with flow cytometry.
3. Untransfected CT26 cells surface (green line) and transfected Human GUCY2C CT26 stable cells surface (red line) were stained with anti-GUCY2C antibody (2µg/1*10^6 cells), washed and then followed by FITC-conjugated Goat Anti-Mouse IgG(H+L) antibody and analyzed with flow cytometry.
Application
ELISA, FCM
Recommended Dose
FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The 145 kDa plasma membrane form of GC-C contains sialic acid and galactose residues, while a differencially glycosylated 130 Kda form is a high mannose form that is resident in the endoplasmic reticulum and may serve as the precursor for the cell surface form.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundReceptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human GUCY2C Protein
Antigen Species
Human
Gene ID
2984
Uniprot ID
Biology Area
Immunology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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