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Synonyms: WSN2, Type I keratin Ka13, type I cytoskeletal 13, MGC3781, MGC161462, Krt1-13, Krt-1.13, KRT 13, Keratin-13, keratin type I cytoskeletal 13, Keratin 13, Keratin, Ka13, K1C13_HUMAN, K13, Cytokeratin-13, Cytokeratin 13, CK-13, CK13, 47 kDa cytokeratin
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
| Description | Anti-KRT13 Antibody (2C427) is a Rabbit antibody targeting KRT13. Anti-KRT13 Antibody (2C427) can be used in ICC,IHC,WB. |
| Synonyms | WSN2, Type I keratin Ka13, type I cytoskeletal 13, MGC3781, MGC161462, Krt1-13, Krt-1.13, KRT 13, Keratin-13, keratin type I cytoskeletal 13, Keratin 13, Keratin, Ka13, K1C13_HUMAN, K13, Cytokeratin-13, Cytokeratin 13, CK-13, CK13, 47 kDa cytokeratin |
| Ig Type | IgG |
| Clone | 2C427 |
| Reactivity | Human,Mouse,zebrafish |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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