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Anti-PPP3CA Antibody (7H104)
Catalog No. TMAB-11692 Copy Product Info
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Anti-PPP3CA Antibody (7H104) is a Rabbit antibody targeting PPP3CA. Anti-PPP3CA Antibody (7H104) can be used in WB,ICC/IF,FCM.
Anti-PPP3CA Antibody (7H104)
Copy Product Info🥰Excellent
Catalog No. TMAB-11692
Anti-PPP3CA Antibody (7H104) is a Rabbit antibody targeting PPP3CA. Anti-PPP3CA Antibody (7H104) can be used in WB,ICC/IF,FCM.
Anti-PPP3CA Antibody
(7H104)
(7H104)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PPP3CA Antibody (7H104) is a Rabbit antibody targeting PPP3CA. Anti-PPP3CA Antibody (7H104) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 7H104 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with PPP3CA monoclonal antibody, unconjugated (TMAB-11692) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle. |
| Tissue Specificity | Interacts with CHP1 and CHP2. Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with CRTC2, MYOZ1, MYOZ2 and MYOZ3. Interacts with DNM1L; the interaction dephosphorylates DNM1L and regulates its translocation to mitochondria. Interacts with CMYA5; this interaction represses calcineurin activity in muscle. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Calcineurin, also known as protein phosphatase 2B (PP2B), is a calmodulin-dependent, calcium-activated, serine/threonine protein phosphatase composed of a catalytic subunit (calcineurin A) and a tightly bound regulatory subunit (calcineurin B). Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. |
| Immunogen | A synthesized peptide: human PPP3CA |
| Antigen Species | Human |
| Gene Name | PPP3CA |
| Gene ID | |
| Protein Name | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
| Uniprot ID | |
| Function | Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. |
| Molecular Weight | Theoretical: 59 kDa. Actual: 59 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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