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Anti-PPP3CA Antibody (7H104)

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Catalog No. TMAB-11692

Anti-PPP3CA Antibody (7H104) is a Rabbit antibody targeting PPP3CA. Anti-PPP3CA Antibody (7H104) can be used in WB,ICC/IF,FCM.

Anti-PPP3CA Antibody (7H104)

Anti-PPP3CA Antibody (7H104)

😃Good
Catalog No. TMAB-11692
Anti-PPP3CA Antibody (7H104) is a Rabbit antibody targeting PPP3CA. Anti-PPP3CA Antibody (7H104) can be used in WB,ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PPP3CA Antibody (7H104) is a Rabbit antibody targeting PPP3CA. Anti-PPP3CA Antibody (7H104) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
7H104
Reactivity
Human,Mouse,Rat
Application
WB
ICC/IF
FCM
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Note=Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.
Tissue SpecificityInteracts with CHP1 and CHP2. Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with CRTC2, MYOZ1, MYOZ2 and MYOZ3. Interacts with DNM1L; the interaction dephosphorylates DNM1L and regulates its translocation to mitochondria. Interacts with CMYA5; this interaction represses calcineurin activity in muscle.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCalcineurin, also known as protein phosphatase 2B (PP2B), is a calmodulin-dependent, calcium-activated, serine/threonine protein phosphatase composed of a catalytic subunit (calcineurin A) and a tightly bound regulatory subunit (calcineurin B). Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.
Antigen Details
Immunogen
A synthesized peptide: human PPP3CA
Antigen Species
Human
Gene Name
PPP3CA
Gene ID
5530
Protein Name
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Uniprot ID
Q08209
Function
Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1.
Chemical Properties
Molecular WeightTheoretical: 59 kDa. Actual: 59 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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