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Anti-GCLM Antibody (9L9)

Catalog No. TMAB-06389 Copy Product Info
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Anti-GCLM Antibody (9L9) is a Rabbit antibody targeting GCLM. Anti-GCLM Antibody (9L9) can be used in WB.

Anti-GCLM Antibody (9L9)

Copy Product Info
🥰Excellent
Catalog No. TMAB-06389

Anti-GCLM Antibody (9L9) is a Rabbit antibody targeting GCLM. Anti-GCLM Antibody (9L9) can be used in WB.

Anti-GCLM Antibody
(9L9)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GCLM Antibody (9L9) is a Rabbit antibody targeting GCLM. Anti-GCLM Antibody (9L9) can be used in WB.
Ig Type
IgG
Clone
9L9
Reactivity
Human,Mouse,Rat
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with GCLM monoclonal antibody, unconjugated (TMAB-06389) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytosol
Tissue SpecificityIn all tissues examined. Highest levels in skeletal muscle.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGlutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Antigen Details
Immunogen
A synthesized peptide: human GCLM
Antigen Species
Human
Gene Name
GCLM
Gene ID
Protein Name
Glutamate--cysteine ligase regulatory subunit
Uniprot ID
Function
This protein is involved in step 1 of the subpathway that synthesizes glutathione from L-cysteine and L-glutamate.
Chemical Properties
Molecular WeightTheoretical: 31 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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