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Anti-CD8 alpha Antibody (9M947)
😃Good
Catalog No. TMAB-04071
Anti-CD8 alpha Antibody (9M947) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (9M947) can be used in IF, IHC-Fr, IHC-P, WB.
Anti-CD8 alpha Antibody (9M947)
Anti-CD8 alpha Antibody (9M947)
😃Good
Catalog No. TMAB-04071
Anti-CD8 alpha Antibody (9M947) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (9M947) can be used in IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD8 alpha Antibody (9M947) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (9M947) can be used in IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 9M947 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | IF=1:200-500; IHC-Fr=1:200-500; IHC-P=1:200-500; WB=1:1000-5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] |
| Immunogen | KLH conjugated synthetic peptide: mouse CD8 alpha |
| Antigen Species | Mouse |
| Gene Name | CD8A |
| Gene ID | |
| Protein Name | T-cell surface glycoprotein CD8 alpha chain |
| Uniprot ID | |
| Function | Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. |
| Molecular Weight | Theoretical: 27 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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