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Anti-Mast Cell Tryptase Antibody (3T990)
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Catalog No. TMAB-08627
Anti-Mast Cell Tryptase Antibody (3T990) is a Rabbit antibody targeting Mast Cell Tryptase. Anti-Mast Cell Tryptase Antibody (3T990) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Mast Cell Tryptase Antibody (3T990)
Anti-Mast Cell Tryptase Antibody (3T990)
😃Good
Catalog No. TMAB-08627
Anti-Mast Cell Tryptase Antibody (3T990) is a Rabbit antibody targeting Mast Cell Tryptase. Anti-Mast Cell Tryptase Antibody (3T990) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Mast Cell Tryptase Antibody (3T990) is a Rabbit antibody targeting Mast Cell Tryptase. Anti-Mast Cell Tryptase Antibody (3T990) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 3T990 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-5000; IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Note=Released from the secretory granules upon mast cell activation. |
| Tissue Specificity | Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide: human Tryptase 1 |
| Antigen Species | Human |
| Gene Name | TPSAB1 |
| Gene ID | |
| Protein Name | Tryptase alpha/beta-1 |
| Uniprot ID | |
| Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. |
| Molecular Weight | Theoretical: 23 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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