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Anti-5 Lipoxygenase Antibody (9G852) is a Rabbit antibody targeting 5 Lipoxygenase. Anti-5 Lipoxygenase Antibody (9G852) can be used in IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
| Description | Anti-5 Lipoxygenase Antibody (9G852) is a Rabbit antibody targeting 5 Lipoxygenase. Anti-5 Lipoxygenase Antibody (9G852) can be used in IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 9G852 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IF=1:200-500; IHC-Fr=1:200-500; IHC-P=1:200-500; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. |
| Immunogen | A synthesized peptide: human 5 Lipoxygenase |
| Antigen Species | Human |
| Gene Name | ALOX5 |
| Gene ID | |
| Protein Name | Polyunsaturated fatty acid 5-lipoxygenase |
| Uniprot ID | |
| Function | Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes. |
| Molecular Weight | Theoretical: 78 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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