Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-FOXO3 Antibody (6R502)
😃Good
Catalog No. TMAC-01551
Alias MGC31925, MGC12739, FOXO3A, FOX O3A, Forkhead in rhabdomyosarcoma-like 1, Forkhead homolog (rhabdomyosarcoma) like 1, Forkhead Drosophila homolog of in rhabdomyosarcoma like 1, Forkhead box O3A, Forkhead box O3, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1, FKHRL1P2, FKHRL1, FKHRL 1, FKHR2, DKFZp781A0677, AF6q21
Anti-FOXO3 Antibody (6R502) is a Rabbit antibody targeting FOXO3. Anti-FOXO3 Antibody (6R502) can be used in WB,ICC/IF.
Anti-FOXO3 Antibody (6R502)
Anti-FOXO3 Antibody (6R502)
😃Good
Catalog No. TMAC-01551Alias MGC31925, MGC12739, FOXO3A, FOX O3A, Forkhead in rhabdomyosarcoma-like 1, Forkhead homolog (rhabdomyosarcoma) like 1, Forkhead Drosophila homolog of in rhabdomyosarcoma like 1, Forkhead box O3A, Forkhead box O3, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1, FKHRL1P2, FKHRL1, FKHRL 1, FKHR2, DKFZp781A0677, AF6q21
Anti-FOXO3 Antibody (6R502) is a Rabbit antibody targeting FOXO3. Anti-FOXO3 Antibody (6R502) can be used in WB,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-FOXO3 Antibody (6R502) is a Rabbit antibody targeting FOXO3. Anti-FOXO3 Antibody (6R502) can be used in WB,ICC/IF. |
| Synonyms | MGC31925, MGC12739, FOXO3A, FOX O3A, Forkhead in rhabdomyosarcoma-like 1, Forkhead homolog (rhabdomyosarcoma) like 1, Forkhead Drosophila homolog of in rhabdomyosarcoma like 1, Forkhead box O3A, Forkhead box O3, Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1, FKHRL1P2, FKHRL1, FKHRL 1, FKHR2, DKFZp781A0677, AF6q21 |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of FOXO3A on different lysates using anti- FOXO3A antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3, Lane 2: PC-12, Lane 3: MCF-7. 2. ICC staining FOXO3A in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining FOXO3A in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining FOXO3A in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | FKHRL1 (forkhead in rhabdomyosarcoma-like 1), also known as FOXO3 (forkheadbox O3) or FOXO3A, is a 673 amino acid transcriptional activator thatbelongs to the FKHR subfamily of forkhead transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 at Threonine 32 and Serine 253. Phosphorylation by Akt1 negatively regulates FKHRL1 by promoting its export from the nucleus. Phosphorylated FKHRL1 associates with 14-3-3 proteins and this complex is retained in the cytoplasm. Growth factor withdrawal stimulates FKHRL1 dephosphorylation and nuclear translocation, leading to FKHR-induced gene-specific transcriptional activation. Within the nucleus, dephosphorylated FKHRL1 triggers apoptosis by inducing the expression of genes that are critical for cell death. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 71 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-FOXO3 Antibody (6R502) | purchase Anti-FOXO3 Antibody (6R502) | Anti-FOXO3 Antibody (6R502) cost | order Anti-FOXO3 Antibody (6R502) | Anti-FOXO3 Antibody (6R502) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.