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Anti-Menin Antibody (3A208)
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Catalog No. TMAB-08749
Anti-Menin Antibody (3A208) is a Rabbit antibody targeting Menin. Anti-Menin Antibody (3A208) can be used in WB,IP.
Anti-Menin Antibody (3A208)
Anti-Menin Antibody (3A208)
😃Good
Catalog No. TMAB-08749
Anti-Menin Antibody (3A208) is a Rabbit antibody targeting Menin. Anti-Menin Antibody (3A208) can be used in WB,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Menin Antibody (3A208) is a Rabbit antibody targeting Menin. Anti-Menin Antibody (3A208) can be used in WB,IP. |
| Ig Type | IgG |
| Clone | 3A208 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation. |
| Tissue Specificity | Ubiquitous. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. |
| Immunogen | A synthesized peptide: human Menin |
| Antigen Species | Human |
| Gene Name | MEN1 |
| Gene ID | |
| Protein Name | MCM3 |
| Uniprot ID | |
| Function | Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair. |
| Molecular Weight | Theoretical: 68 kDa. Actual: 68 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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