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Anti-PNKP Antibody (8B76)
😃Good
Catalog No. TMAB-11594
Anti-PNKP Antibody (8B76) is a Rabbit antibody targeting PNKP. Anti-PNKP Antibody (8B76) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-PNKP Antibody (8B76)
Anti-PNKP Antibody (8B76)
😃Good
Catalog No. TMAB-11594
Anti-PNKP Antibody (8B76) is a Rabbit antibody targeting PNKP. Anti-PNKP Antibody (8B76) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PNKP Antibody (8B76) is a Rabbit antibody targeting PNKP. Anti-PNKP Antibody (8B76) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 8B76 |
| Reactivity | Human |
| Application | |
| Recommended Dose | ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:100-200; IHC-P=1:100-200; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in many tissues with highest expression in spleen and testis, and lowest expression in small intestine (PubMed:10446192). Expressed in higher amount in pancreas, heart and kidney and at lower levels in brain, lung and liver (PubMed:10446193). |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. |
| Immunogen | A synthesized peptide: human PNKP |
| Antigen Species | Human |
| Gene Name | PNKP |
| Gene ID | |
| Protein Name | Bifunctional polynucleotide phosphatase/kinase |
| Uniprot ID | |
| Function | Catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. Plays an important function in DNA repair following ionizing radiation or oxidative damage. |
| Molecular Weight | Theoretical: 57 kDa. Actual: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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