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Anti-PNKP Antibody (8B76)
Catalog No. TMAB-11594 Copy Product Info
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Anti-PNKP Antibody (8B76) is a Rabbit antibody targeting PNKP. Anti-PNKP Antibody (8B76) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-PNKP Antibody (8B76)
Copy Product Info🥰Excellent
Catalog No. TMAB-11594
Anti-PNKP Antibody (8B76) is a Rabbit antibody targeting PNKP. Anti-PNKP Antibody (8B76) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-PNKP Antibody
(8B76)
(8B76)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PNKP Antibody (8B76) is a Rabbit antibody targeting PNKP. Anti-PNKP Antibody (8B76) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 8B76 |
| Reactivity | Human |
| Verified Activity | 25 ug total protein per lane of various lysates (see on figure) probed with PNKP monoclonal antibody, unconjugated (TMAB-11594) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:100-200; IHC-P=1:100-200; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in many tissues with highest expression in spleen and testis, and lowest expression in small intestine (PubMed:10446192). Expressed in higher amount in pancreas, heart and kidney and at lower levels in brain, lung and liver (PubMed:10446193). |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. |
| Immunogen | A synthesized peptide: human PNKP |
| Antigen Species | Human |
| Gene Name | PNKP |
| Gene ID | |
| Protein Name | Bifunctional polynucleotide phosphatase/kinase |
| Uniprot ID | |
| Function | Catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. Plays an important function in DNA repair following ionizing radiation or oxidative damage. |
| Molecular Weight | Theoretical: 57 kDa. Actual: 57 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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