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Anti-CD146/MCAM Antibody (9Q805)
(Synonyms: MUC18, melanoma cell adhesion molecule, CD146) Copy Product Info
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Synonyms: MUC18, melanoma cell adhesion molecule, CD146
Catalog No. TMAH-00170 Copy Product Info
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Anti-CD146/MCAM Antibody (9Q805) is an antibody targeting CD146/MCAM. Anti-CD146/MCAM Antibody (9Q805) can be used in ELISA,FCM,IF,IHC,WB.
Anti-CD146/MCAM Antibody
(9Q805)
(9Q805)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD146/MCAM Antibody (9Q805) is an antibody targeting CD146/MCAM. Anti-CD146/MCAM Antibody (9Q805) can be used in ELISA,FCM,IF,IHC,WB. |
| Synonyms | MUC18, melanoma cell adhesion molecule, CD146 |
| Ig Type | Rabbit IgG |
| Clone | 9Q805 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:500; IF:1:30-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Detected in endothelial cells in vascular tissue throughout the body. May appear at the surface of neural crest cells during their embryonic migration. Appears to be limited to vascular smooth muscle in normal adult tissues. Associated with tumor progress |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide |
| Antigen Species | Human |
| Gene Name | MCAM |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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