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Anti-SAE1 Antibody (2I706)

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Catalog No. TMAB-12472 Copy Product Info
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Anti-SAE1 Antibody (2I706) is a Rabbit antibody targeting SAE1. Anti-SAE1 Antibody (2I706) can be used in WB,ICC/IF,IP,FCM.
Anti-SAE1 Antibody
(2I706)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SAE1 Antibody (2I706) is a Rabbit antibody targeting SAE1. Anti-SAE1 Antibody (2I706) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
Clone
2I706
Reactivity
Human (predicted:Rat)
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityExpression level increases during S phase and drops in G2 phase (at protein level).
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundThe heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Antigen Details
Immunogen
A synthesized peptide: human SAE1
Antigen Species
Human
Gene Name
SAE1
Gene ID
Protein Name
SUMO-activating enzyme subunit 1
Uniprot ID
Function
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
Chemical Properties
Molecular WeightTheoretical: 38 kDa. Actual: 42 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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