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Anti-CRTC3 Antibody (4U400)

😃Good
Catalog No. TMAB-04705

Anti-CRTC3 Antibody (4U400) is a Rabbit antibody targeting CRTC3. Anti-CRTC3 Antibody (4U400) can be used in IF, IHC-Fr, IHC-P, WB.

Anti-CRTC3 Antibody (4U400)

Anti-CRTC3 Antibody (4U400)

😃Good
Catalog No. TMAB-04705
Anti-CRTC3 Antibody (4U400) is a Rabbit antibody targeting CRTC3. Anti-CRTC3 Antibody (4U400) can be used in IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CRTC3 Antibody (4U400) is a Rabbit antibody targeting CRTC3. Anti-CRTC3 Antibody (4U400) can be used in IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
4U400
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IF=1:50-200; IHC-Fr=1:50-200; IHC-P=1:50-200; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Appears to be mainly nuclear.
Tissue SpecificityPredominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTranscriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells.
Antigen Details
Immunogen
A synthesized peptide: human CRTC3
Antigen Species
Human
Gene Name
CRTC3
Gene ID
Protein Name
CREB-regulated transcription coactivator 3
Uniprot ID
Function
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Chemical Properties
Molecular WeightTheoretical: 67 kDa. Actual: 75 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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