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Racotumomab
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Catalog No. T77443Cas No. 946832-34-4
Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.
Racotumomab
Racotumomab
😃Good
Catalog No. T77443Cas No. 946832-34-4
Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $163 | - | In Stock | |
| 5 mg | $496 | - | In Stock | |
| 10 mg | $795 | - | In Stock | |
| 25 mg | $1,180 | - | In Stock | |
| 50 mg | $1,580 | - | In Stock | |
| 100 mg | $2,160 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:> 95%
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Target GM3
Antibody Information
| Description | Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research. |
| In vitro | Inducing a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, racotumomab stimulates cell death[4]. |
| In vivo | In F3II cell (s.c.) mammary tumor mice models, racotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth[2]. Against lung nodules in 3LL cell (s.c.) mice xenograft, racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective[3]. However, in 3LL cell (s.c.) mice xenograft, racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect[3]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | 146.6 kDa |
| Cas No. | 946832-34-4 |
| Isotype | IgG |
Storage & Solubility Information
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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