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Racotumomab
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Catalog No. T77443 Copy Product Info
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Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody. It can specifically induce an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), which is overexpressed in a variety of solid tumors. Racotumomab reacts with gangliosides containing NU-Glycolyl (NeuGc), thioglycosides, and other antigens expressed in tumors. Racotumomab has anti-cancer activity and can be used in the study of lung cancer.
Cas No. 946832-34-4
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $130 | - | In Stock | |
| 5 mg | $397 | - | In Stock | |
| 10 mg | $636 | - | In Stock | |
| 25 mg | $943 | - | In Stock | |
| 50 mg | Preferential | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody. It can specifically induce an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), which is overexpressed in a variety of solid tumors. Racotumomab reacts with gangliosides containing NU-Glycolyl (NeuGc), thioglycosides, and other antigens expressed in tumors. Racotumomab has anti-cancer activity and can be used in the study of lung cancer. |
| In vitro | Inducing a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, racotumomab stimulates cell death[4]. |
| In vivo | In F3II cell (s.c.) mammary tumor mice models, racotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth[2]. Against lung nodules in 3LL cell (s.c.) mice xenograft, racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective[3]. However, in 3LL cell (s.c.) mice xenograft, racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect[3]. |
| Endotoxin | <1.0 EU/mg |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | GM3 |
| Molecular Weight | 146.6 kDa |
| Cas No. | 946832-34-4 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Racotumomab chemical structure | Racotumomab in vivo | Racotumomab in vitro | Racotumomab molecular weight
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