store at low temperature
store at -80°C
Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody. It can specifically induce an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), which is overexpressed in a variety of solid tumors. Racotumomab reacts with gangliosides containing NU-Glycolyl (NeuGc), thioglycosides, and other antigens expressed in tumors. Racotumomab has anti-cancer activity and can be used in the study of lung cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 247.00 | |
5 mg | In stock | $ 647.00 | |
10 mg | In stock | $ 987.00 | |
25 mg | In stock | $ 1,530.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,780.00 |
Description | Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody. It can specifically induce an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), which is overexpressed in a variety of solid tumors. Racotumomab reacts with gangliosides containing NU-Glycolyl (NeuGc), thioglycosides, and other antigens expressed in tumors. Racotumomab has anti-cancer activity and can be used in the study of lung cancer. |
In vitro | Inducing a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, racotumomab stimulates cell death[4]. |
In vivo |
In F3II cell (s.c.) mammary tumor mice models, racotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth[2]. Against lung nodules in 3LL cell (s.c.) mice xenograft, racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective[3]. However, in 3LL cell (s.c.) mice xenograft, racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect[3]. |
Molecular Weight | N/A |
CAS No. | 946832-34-4 |
store at low temperature
store at -80°C
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Racotumomab 946832-34-4 Others inhibitor inhibit