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Racotumomab

Catalog No. T77443 Copy Product Info
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Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.

Racotumomab

Copy Product Info
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Catalog No. T77443

Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.

Racotumomab
Cas No. 946832-34-4
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$163-In Stock
5 mg$496-In Stock
10 mg$795-In Stock
25 mg$1,180-In Stock
50 mg$1,580-In Stock
100 mg$2,160-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.
In vitro
Inducing a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, racotumomab stimulates cell death[4].
In vivo
In F3II cell (s.c.) mammary tumor mice models, racotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth[2].
Against lung nodules in 3LL cell (s.c.) mice xenograft, racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective[3].
However, in 3LL cell (s.c.) mice xenograft, racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect[3].
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetGM3
Chemical Properties
Molecular Weight146.6 kDa
Cas No.946832-34-4
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storage-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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