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Racotumomab

Catalog No. T77443 Copy Product Info
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Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.

Racotumomab

Copy Product Info
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Catalog No. T77443

Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.

Racotumomab
Cas No. 946832-34-4
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$163-In Stock
5 mg$496-In Stock
10 mg$795-In Stock
25 mg$1,180-In Stock
50 mg$1,580-In Stock
100 mg$2,160-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is a mouse γ-type anti-recombinant antibody that specifically induces an antibody response against Neu-glycolyl GM3 ganglioside (NeuGcGM3), overexpressed in various solid tumors. Racotumomab reacts with gangliosides containing Neu-Glycolyl (NeuGc), thioglycosides, and other tumor-expressed antigens, demonstrating anti-cancer activity, and is used in lung cancer research.
In vitro
Inducing a specific humoral and cellular immune response against the NeuGcGM3 ganglioside present in tumor cells, racotumomab stimulates cell death[4].
In vivo
In F3II cell (s.c.) mammary tumor mice models, racotumomab (50 μg/dose, i.p.) together with Keyhole limpet hemocyanin (KLH) inhibits tumor growth[2].
Against lung nodules in 3LL cell (s.c.) mice xenograft, racotumomab (50 μg/dose, s.c.) together with Pemetrexed (100 mg/kg) is highly effective[3].
However, in 3LL cell (s.c.) mice xenograft, racotumomab (50-200 μg/dose, s.c.) shows no significant antitumor effect[3].
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetGM3
Chemical Properties
Molecular Weight146.6 kDa
Cas No.946832-34-4
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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