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Anti-TLR2 Antibody (7Y355)
(Synonyms: toll-like receptor 2) Copy Product Info
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Synonyms: toll-like receptor 2
Catalog No. TMAB-01853 Copy Product Info
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Anti-TLR2 Antibody (7Y355) is a Rabbit antibody targeting TLR2. Anti-TLR2 Antibody (7Y355) can be used in FCM, WB.
Anti-TLR2 Antibody
(7Y355)
(7Y355)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $153 | 7-10 days | 7-10 days | |
| 50 μL | $273 | 7-10 days | 7-10 days | |
| 100 μL | $487 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TLR2 Antibody (7Y355) is a Rabbit antibody targeting TLR2. Anti-TLR2 Antibody (7Y355) can be used in FCM, WB. |
| Synonyms | toll-like receptor 2 |
| Ig Type | IgG |
| Clone | 7Y355 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | FCM=1 μg/Test; WB=1:1000-5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in peripheral blood leukocytes, in particular in monocytes, in bone marrow, lymph node and in spleen. Also detected in lung and in fetal liver. Levels are low in other tissues. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]. |
| Immunogen | Recombinant Protein: full length protein of human TLR2 |
| Antigen Species | Human |
| Gene Name | TLR2 |
| Gene ID | |
| Protein Name | Toll-like receptor 2 |
| Uniprot ID | |
| Biology Area | Inflammatory mediators,Receptors,Macrophage / Inflamm.,TLR Signaling,Defensin,Transmembrane |
| Function | Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. |
| Molecular Weight | Theoretical: 84 kDa. Actual: 100 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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