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Anti-PTPN2 Antibody (2V471)
😃Good
Catalog No. TMAB-11928
Anti-PTPN2 Antibody (2V471) is a Mouse antibody targeting PTPN2. Anti-PTPN2 Antibody (2V471) can be used in WB,IHC-P,IHC-Fr,IF,FCM,FCM.
Anti-PTPN2 Antibody (2V471)
Anti-PTPN2 Antibody (2V471)
😃Good
Catalog No. TMAB-11928
Anti-PTPN2 Antibody (2V471) is a Mouse antibody targeting PTPN2. Anti-PTPN2 Antibody (2V471) can be used in WB,IHC-P,IHC-Fr,IF,FCM,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PTPN2 Antibody (2V471) is a Mouse antibody targeting PTPN2. Anti-PTPN2 Antibody (2V471) can be used in WB,IHC-P,IHC-Fr,IF,FCM,FCM. |
| Ig Type | IgG1, Kappa |
| Clone | 2V471 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | [Isoform 2]: Nucleus. Cytoplasm. Cell membrane. Note=Predominantly localizes to chromatin (By similarity). Able to shuttle between the nucleus and the cytoplasm and to dephosphorylate plasma membrane receptors (PubMed:9488479). Recruited by activated ITGA1 at the plasma membrane. {ECO:0000250, ECO:0000269|PubMed:9488479}. |
| Tissue Specificity | Ubiquitously expressed. Isoform 2 is probably the major isoform. Isoform 1 is expressed in T-cells and in placenta. |
| Construction | Recombinant Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011] |
| Gene Name | PTPN2 |
| Gene ID | |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 2 |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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