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Anti-PTPN2 Antibody (2V471)

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Catalog No. TMAB-11928 Copy Product Info
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Anti-PTPN2 Antibody (2V471) is a Mouse antibody targeting . Anti-PTPN2 Antibody (2V471) can be used in WB,IHC-P,IHC-F,IF,FCM.
Anti-PTPN2 Antibody (2V471)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PTPN2 Antibody (2V471) is a Mouse antibody targeting . Anti-PTPN2 Antibody (2V471) can be used in WB,IHC-P,IHC-F,IF,FCM.
Ig Type
IgG1, Kappa
Clone
2V471
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,FCM=1:50-100
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular Localization[Isoform 2]: Nucleus. Cytoplasm. Cell membrane. Note=Predominantly localizes to chromatin (By similarity). Able to shuttle between the nucleus and the cytoplasm and to dephosphorylate plasma membrane receptors (PubMed:9488479). Recruited by activated ITGA1 at the plasma membrane. {ECO:0000250, ECO:0000269|PubMed:9488479}.
Tissue SpecificityUbiquitously expressed. Isoform 2 is probably the major isoform. Isoform 1 is expressed in T-cells and in placenta.
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011]
Antigen Details
Gene Name
PTPN2
Gene ID
Protein Name
Tyrosine-protein phosphatase non-receptor type 2
Chemical Properties
Molecular WeightActual: 50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-PTPN2 Antibody (2V471) chemical structure | Anti-PTPN2 Antibody (2V471) molecular weight