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Anti-TFE3 Antibody (5K387)

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Catalog No. TMAB-13469

Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF.

Anti-TFE3 Antibody (5K387)

Anti-TFE3 Antibody (5K387)

😃Good
Catalog No. TMAB-13469
Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
5K387
Reactivity
Human
Application
Recommended Dose
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityUbiquitous in fetal and adult tissues.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTranscription factor that acts as a master regulator of lysosomal biogenesis and immune response . Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF.
Antigen Details
Immunogen
A synthesized peptide: human TFE3
Antigen Species
Human
Gene Name
TFE3
Gene ID
Protein Name
Transcription factor E3
Uniprot ID
Function
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Chemical Properties
Molecular WeightTheoretical: 62 kDa. Actual: 62 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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