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Anti-TFE3 Antibody (5K387)
Catalog No. TMAB-13469 Copy Product Info
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Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF.
Anti-TFE3 Antibody (5K387)
Copy Product Info🥰Excellent
Catalog No. TMAB-13469
Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF.
Anti-TFE3 Antibody
(5K387)
(5K387)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TFE3 Antibody (5K387) is a Rabbit antibody targeting TFE3. Anti-TFE3 Antibody (5K387) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 5K387 |
| Reactivity | Human |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded Human Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with TFE3 Monoclonal Antibody, Unconjugated (TMAB-13469) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Ubiquitous in fetal and adult tissues. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response . Specifically recognizes and binds E-box sequences (5'-CANNTG-3'); efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. |
| Immunogen | A synthesized peptide: human TFE3 |
| Antigen Species | Human |
| Gene Name | TFE3 |
| Gene ID | |
| Protein Name | Transcription factor E3 |
| Uniprot ID | |
| Function | Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
| Molecular Weight | Theoretical: 62 kDa. Actual: 62 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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