IL-33 Protein, Human, Recombinant V2

Name: IL-33 Protein, Human, Recombinant V2
Brand: TargetMol
SKU: TMPY-00861U
Rating: 4.5 (1 reviews)

(Synonyms: NF-HEV, NFEHEV, interleukin 33, IL1F11, DVS27, C9orf26) Copy Product Info

Synonyms: NF-HEV, NFEHEV, interleukin 33, IL1F11, DVS27, C9orf26

Catalog No. TMPY-00861U Copy Product Info

IL-33 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is O95760.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$57	7-10 days	7-10 days
10 µg	$91	7-10 days	7-10 days
20 µg	$147	7-10 days	7-10 days
50 µg	$277	7-10 days	7-10 days
100 µg	$447	7-10 days	7-10 days
200 µg	$763	7-10 days	7-10 days
500 µg	$1,530	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 0.5 ng/ml, measured by a cell proliferation assay using D10S cells, corresponding to a specific activity of > 2.0 × 10^6 units/mg.
Description	IL-33 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is O95760.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	O95760
Construction	Ser112-Thr270
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	NF-HEV, NFEHEV, interleukin 33, IL1F11, DVS27, C9orf26
Research Background	Interleukin-33 (IL-33) is a proinflammatory cytokine that belongs to the IL-1 family. IL-33 is expressed in a variety of cells, including epithelial and endothelial cells, smooth muscle cells, macrophages and fibroblasts. The primary receptors for IL-33 are ST2 and IL-1 receptor accessory protein (IL-1RAcP), both of which belong to the IL-1 receptor family. IL-33 is localized to the nucleus of resting cells where it binds to chromatin in the H2A-H2B histone complex as a transcriptional suppressor. IL-33 is secreted by cells during injury which induces a T-helper 2 type inflammatory response. Evidence suggests IL-33 plays a role in autoimmune disease. IL-33’s interaction with ST2 can drive allergic pathology and IL-33 has been reported to play a role in the development of rheumatoid arthritis and systemic lupus erythematosus.

Chemical Properties

Molecular Weight

18.0 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.