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Anti-HMBS Antibody (1J975) (Synonyms: UPS, Pre-Uroporphyrinogen Synthase, Porphobilinogen Deaminase, PBG-D, ...)

Catalog No. TMAH-00557 Copy Product Info
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Anti-HMBS Antibody (1J975) is an antibody targeting HMBS. Anti-HMBS Antibody (1J975) can be used in ELISA,WB.

Anti-HMBS Antibody (1J975)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00557
Synonyms UPS, Pre-Uroporphyrinogen Synthase, Porphobilinogen Deaminase, PBG-D, PBGD, Hydroxymethylbilane Synthase, HMBS

Anti-HMBS Antibody (1J975) is an antibody targeting HMBS. Anti-HMBS Antibody (1J975) can be used in ELISA,WB.

Anti-HMBS Antibody
(1J975)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HMBS Antibody (1J975) is an antibody targeting HMBS. Anti-HMBS Antibody (1J975) can be used in ELISA,WB.
SynonymsUPS, Pre-Uroporphyrinogen Synthase, Porphobilinogen Deaminase, PBG-D, PBGD, Hydroxymethylbilane Synthase, HMBS
Ig Type
Rabbit IgG
Clone
1J975
Reactivity
Human
Verified Activity
Western Blot
-Positive WB detected in: MCF-7 whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, THP-1 whole cell lysate, U937 whole cell lysate
-All lanes: HMBS antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 40, 38, 35, 34kDa
-Observed band size: 36-55 kDa
Application
Recommended Dose
WB:1:500-1:2000.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm.
Tissue Specificity[Isoform 1]: Is ubiquitously expressed.; [Isoform 2]: Is found only in erythroid cells.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundAs part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen. The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled. In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human HMBS
Antigen Species
Human
Gene Name
HMBS
Gene ID
Uniprot ID
Biology Area
Cell biology, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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