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Anti-HMBS Antibody (1J975) is an antibody targeting HMBS. Anti-HMBS Antibody (1J975) can be used in ELISA, WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $347 | 7-10 days |
Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, WB Reactivity: Human |
Alias | UPS, Pre-Uroporphyrinogen Synthase, Porphobilinogen Deaminase, PBG-D, PBGD, Hydroxymethylbilane Synthase, HMBS |
Ig Type | Rabbit IgG |
Clone | 1J975 |
Reactivity | Human |
Verified Activity | Western Blot -Positive WB detected in: MCF-7 whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, THP-1 whole cell lysate, U937 whole cell lysate -All lanes: HMBS antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 40, 38, 35, 34kDa -Observed band size: 36-55 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:2000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cytoplasm. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen. The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled. In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human HMBS |
Antigen Species | Human |
Gene ID | 3145 |
Uniprot ID | |
Biology Area | Cell biology, Metabolism, Signal transduction |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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