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Anti-HMBS Antibody (1J975)

😃Good
Catalog No. TMAH-00557
Alias UPS, Pre-Uroporphyrinogen Synthase, Porphobilinogen Deaminase, PBG-D, PBGD, Hydroxymethylbilane Synthase, HMBS

Anti-HMBS Antibody (1J975) is an antibody targeting HMBS. Anti-HMBS Antibody (1J975) can be used in ELISA, WB.

Anti-HMBS Antibody (1J975)

Anti-HMBS Antibody (1J975)

😃Good
Catalog No. TMAH-00557Alias UPS, Pre-Uroporphyrinogen Synthase, Porphobilinogen Deaminase, PBG-D, PBGD, Hydroxymethylbilane Synthase, HMBS
Anti-HMBS Antibody (1J975) is an antibody targeting HMBS. Anti-HMBS Antibody (1J975) can be used in ELISA, WB.
Pack SizePriceAvailabilityQuantity
50 μL$207 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, WB

Reactivity: Human
AliasUPS, Pre-Uroporphyrinogen Synthase, Porphobilinogen Deaminase, PBG-D, PBGD, Hydroxymethylbilane Synthase, HMBS
Ig Type
Rabbit IgG
Clone
1J975
Reactivity
Human
Verified Activity
Western Blot
-Positive WB detected in: MCF-7 whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, THP-1 whole cell lysate, U937 whole cell lysate
-All lanes: HMBS antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 40, 38, 35, 34kDa
-Observed band size: 36-55 kDa
Application
ELISA, WB
Recommended Dose
WB:1:500-1:2000.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundAs part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen. The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled. In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human HMBS
Antigen Species
Human
Gene ID
3145
Uniprot ID
Biology Area
Cell biology, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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