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Anti-Cullin 2 Antibody (3T657)
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Catalog No. TMAB-04786
Anti-Cullin 2 Antibody (3T657) is a Rabbit antibody targeting Cullin 2. Anti-Cullin 2 Antibody (3T657) can be used in WB,ICC/IF,IP,FCM.
Anti-Cullin 2 Antibody (3T657)
Anti-Cullin 2 Antibody (3T657)
😃Good
Catalog No. TMAB-04786
Anti-Cullin 2 Antibody (3T657) is a Rabbit antibody targeting Cullin 2. Anti-Cullin 2 Antibody (3T657) can be used in WB,ICC/IF,IP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Cullin 2 Antibody (3T657) is a Rabbit antibody targeting Cullin 2. Anti-Cullin 2 Antibody (3T657) can be used in WB,ICC/IF,IP,FCM. |
| Ig Type | IgG |
| Clone | 3T657 |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. |
| Immunogen | A synthesized peptide: human Cullin 2 |
| Antigen Species | Human |
| Gene Name | CUL2 |
| Gene ID | |
| Protein Name | Cullin-2 |
| Uniprot ID | |
| Function | Core component of multiple cullin-RING-based ECS(ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligasecomplexes, which mediate the ubiquitination of target proteins. Mayserve as a rigid scaffold in the complex and may contribute tocatalysis through positioning of the substrate and theubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligaseactivity of the complex is dependent on the neddylation of thecullin subunit and is inhibited by the association of thedeneddylated cullin subunit with TIP120A/CAND1 (By similarity). Thefunctional specificity of the ECS complex depends on the substraterecognition component. ECS(VHL) mediates the ubiquitination ofhypoxia-inducible factor (HIF). |
| Molecular Weight | Theoretical: 87 kDa. Actual: 87 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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