CD19 Protein, Human, Recombinant (CHO, hFc)

Name: CD19 Protein, Human, Recombinant (CHO, hFc)
Brand: TargetMol
SKU: TMPY-05427U
Rating: 4.5 (1 reviews)

(Synonyms: CVID3, CD19 molecule, B4) Copy Product Info

Synonyms: CVID3, CD19 molecule, B4

Catalog No. TMPY-05427U Copy Product Info

CD19 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is P15391.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$154	7-10 days	7-10 days
10 µg	$246	7-10 days	7-10 days
20 µg	$397	7-10 days	7-10 days
50 µg	$697	7-10 days	7-10 days
100 µg	$1,110	7-10 days	7-10 days
200 µg	$1,770	7-10 days	7-10 days
500 µg	$3,100	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human FMC63 at 2 μg/ml (100 μl/well) can bind Human CD19-Fc. The ED50 of Recombinant Human CD19-Fc is 55.28 ng/ml. Loaded Anti-Human CD19 mAb-Fc on AMC Biosensor, can bind Human CD19-FC with an affinity constant of 2.72 nM as determined in BLI assay.
Description	CD19 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is P15391.
Species	Human
Expression System	CHO Cells
Tag	C-Fc
Accession Number	P15391
Construction	Pro20-Lys291
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	CVID3, CD19 molecule, B4
Research Background	CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Chemical Properties

Molecular Weight

57.3 kDa (Predicted); 80-95 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.