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Anti-CD11a Antibody (3M379)

Catalog No. TMAB-03825 Copy Product Info
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Anti-CD11a Antibody (3M379) is a Rabbit antibody targeting CD11a. Anti-CD11a Antibody (3M379) can be used in FCM.

Anti-CD11a Antibody (3M379)

Copy Product Info
🥰Excellent
Catalog No. TMAB-03825

Anti-CD11a Antibody (3M379) is a Rabbit antibody targeting CD11a. Anti-CD11a Antibody (3M379) can be used in FCM.

Anti-CD11a Antibody
(3M379)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD11a Antibody (3M379) is a Rabbit antibody targeting CD11a. Anti-CD11a Antibody (3M379) can be used in FCM.
Ig Type
IgG
Clone
3M379
Reactivity
Human
Verified Activity
The THP-1 (H) cells were incubated in 5% BSA to block non-specific protein-protein interactions (30 min at r. T.). Primary Antibody (green): Rabbit Anti-CD11a antibody (TMAB-03825): 1 μg/10^6 cells; Secondary Antibody (white blue): Goat anti-Rabbit IgG-FITC: 1 μg/test. Isotype Control (orange): Rabbit IgG. Blank control (black): PBS. Acquisition of 20,000 events was performed.
Application
Recommended Dose
FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityLeukocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
A synthesized peptide: human CD11a
Antigen Species
Human
Gene Name
ITGAL
Gene ID
Protein Name
Integrin alpha-L
Uniprot ID
Function
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Chemical Properties
Molecular WeightTheoretical: 126 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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