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Anti-BCL11A Antibody (7U151)

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Catalog No. TMAB-03048 Copy Product Info
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Anti-BCL11A Antibody (7U151) is a Rabbit antibody targeting BCL11A. Anti-BCL11A Antibody (7U151) can be used in WB,ICC/IF,FCM.
Anti-BCL11A Antibody
(7U151)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BCL11A Antibody (7U151) is a Rabbit antibody targeting BCL11A. Anti-BCL11A Antibody (7U151) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
7U151
Reactivity
Human (predicted:Mouse,Rat)
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.
Tissue SpecificityExpressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundAssociated with the BAF SWI/SNF chromatin remodeling complex.Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene.Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin (HbF) level.
Antigen Details
Immunogen
A synthesized peptide: human BCL 11A
Antigen Species
Human
Gene Name
BCL11A
Gene ID
Protein Name
B-cell lymphoma/leukemia 11A
Uniprot ID
Function
Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.
Chemical Properties
Molecular WeightTheoretical: 91 kDa. Actual: 110 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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