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Anti-GAD67 Antibody (1N825) (Synonyms: SCP, glutamate decarboxylase 1 (brain, 67kDa), GAD, CPSQ1)
Catalog No. TMAC-01594 Copy Product Info
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Anti-GAD67 Antibody (1N825) is a Rabbit antibody targeting GAD67. Anti-GAD67 Antibody (1N825) can be used in IP,WB.
Anti-GAD67 Antibody (1N825)
Copy Product Info🥰Excellent
Catalog No. TMAC-01594
Synonyms SCP, glutamate decarboxylase 1 (brain, 67kDa), GAD, CPSQ1
Anti-GAD67 Antibody (1N825) is a Rabbit antibody targeting GAD67. Anti-GAD67 Antibody (1N825) can be used in IP,WB.
Anti-GAD67 Antibody
(1N825)
(1N825)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GAD67 Antibody (1N825) is a Rabbit antibody targeting GAD67. Anti-GAD67 Antibody (1N825) can be used in IP,WB. |
| Synonyms | SCP, glutamate decarboxylase 1 (brain, 67kDa), GAD, CPSQ1 |
| Ig Type | IgG |
| Clone | 1N825 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of GAD67 on Hela cells lysates using anti-GAD67 antibody at 1/500 dilution.  |
| Application | |
| Recommended Dose | WB: 1:500-1000; IP: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (g-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production. The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal. Due to alternative splicing, two isoforms exist for GAD-67, the predominant GAD-67 form and the minor GAD-25 form. GAD-25 is not expressed in brain but can be found in a variety of endocrine tissues. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 67 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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