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Anti-ITGAL Antibody (1J385)
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Catalog No. TMAC-00647
Alias CD11a
Anti-ITGAL Antibody (1J385) is a Rabbit antibody targeting ITGAL. Anti-ITGAL Antibody (1J385) can be used in WB,ICC/IF,IHC,IP,FCM.
Anti-ITGAL Antibody (1J385)
Anti-ITGAL Antibody (1J385)
😃Good
Catalog No. TMAC-00647Alias CD11a
Anti-ITGAL Antibody (1J385) is a Rabbit antibody targeting ITGAL. Anti-ITGAL Antibody (1J385) can be used in WB,ICC/IF,IHC,IP,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-ITGAL Antibody (1J385) is a Rabbit antibody targeting ITGAL. Anti-ITGAL Antibody (1J385) can be used in WB,ICC/IF,IHC,IP,FCM. |
| Synonyms | CD11a |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of CD11a on Jurkat cell lysates using anti-CD11a antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11a antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11a antibody. Counter stained with hematoxylin. 4. ICC staining CD11a in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining CD11a in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining CD11a in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. Flow cytometric analysis of K562 cells with CD11a antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 180 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
LFA-1ALFA1ALeukocyte function-associated molecule 1 α chainLeukocyte function-associated molecule 1 alpha chainLeukocyte function-associated molecule 1 a chainLeukocyte adhesion glycoprotein LFA-1 α chain (LFA-1A)Leukocyte adhesion glycoprotein LFA-1 alpha chain (LFA-1A)Leukocyte adhesion glycoprotein LFA-1 a chain (LFA-1A)ITGALIntegrinα-LIntegrinαLIntegrinaLIntegrin α-LIntegrin αLIntegrin alpha-LIntegrin alphaLIntegrin a-LIntegrin aLCD11 antigen-like family member A
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