Anti-Securin Antibody (6U972) is a Rabbit antibody targeting Securin. Anti-Securin Antibody (6U972) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.

IgG

6U972

Human

1. 25 ug total protein per lane of various lysates (see on figure) probed with Securin monoclonal antibody, unconjugated (TMAB-12633) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Securin Recombinant  Monoclonal Antibody, Unconjugated (TMAB-12633) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.

FCM=1:50-100; ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; IP=1:20-50; WB=1:500-2000

Monoclonal

A synthesized peptide: human Securin

Human

PTTG1

Securin

Expressed at low level in most tissues, except in adult testis, where it is highly expressed. Overexpressed in many patients suffering from pituitary adenomas, primary epithelial neoplasias, and esophageal cancer.