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Anti-Frizzled-8 Antibody (5A651)

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Catalog No. TMAC-01564

Anti-Frizzled-8 Antibody (5A651) is a Rabbit antibody targeting Frizzled-8. Anti-Frizzled-8 Antibody (5A651) can be used in WB,IHC.

Anti-Frizzled-8 Antibody (5A651)

Anti-Frizzled-8 Antibody (5A651)

😃Good
Catalog No. TMAC-01564
Anti-Frizzled-8 Antibody (5A651) is a Rabbit antibody targeting Frizzled-8. Anti-Frizzled-8 Antibody (5A651) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Frizzled-8 Antibody (5A651) is a Rabbit antibody targeting Frizzled-8. Anti-Frizzled-8 Antibody (5A651) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundReceptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Coreceptor along with RYK of Wnt proteins, such as WNT1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
49849
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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