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Anti-EAAT3 Antibody (2S513) is a Rabbit antibody targeting EAAT3. Anti-EAAT3 Antibody (2S513) can be used in ICC,IF,IHC,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-EAAT3 Antibody (2S513) is a Rabbit antibody targeting EAAT3. Anti-EAAT3 Antibody (2S513) can be used in ICC,IF,IHC,WB. |
Synonyms | Solute carrier family 1, member 1, Solute carrier family 1 member 1, Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1, Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter, system Xag), member 1, Sodium-dependent glutamate/aspartate transporter 3, Sodium dependent glutamate/aspartate transporter 3, SLC1A1, Slc1a 1, Slc1 a1, REAAC1, REAAC 1, Neuronal and epithelial glutamate transporter, MEAAC1, MEAAC 1, GLUTAMATE TRANSPORTER, HIGH-AFFINITY, Excitatory amino-acid carrier 1, Excitatory amino acid transporter3, Excitatory amino acid transporter 3, Excitatory amino acid carrier1, Excitatory amino acid carrier 1, EAAT 3, EAAC1, EAAC 1, EAA3_HUMAN |
Ig Type | IgG |
Clone | 2S513 |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of EAAT3 on mouse liver tissue lysate using anti-EAAT3 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-EAAT3 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-EAAT3 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-EAAT3 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-EAAT3 antibody. Counter stained with hematoxylin. 6. ICC staining EAAT3 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining EAAT3 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. ICC staining EAAT3 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC:IF: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Negatively regulated by ARL6IP5. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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