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Anti-Acetyl-Histone H3.1 (Lys28) Antibody (9L563) is a Rabbit antibody targeting Acetyl-Histone H3.1 (Lys28). Anti-Acetyl-Histone H3.1 (Lys28) Antibody (9L563) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,ChIP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
| Description | Anti-Acetyl-Histone H3.1 (Lys28) Antibody (9L563) is a Rabbit antibody targeting Acetyl-Histone H3.1 (Lys28). Anti-Acetyl-Histone H3.1 (Lys28) Antibody (9L563) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,ChIP,FCM. |
| Ig Type | IgG |
| Clone | 9L563 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; IP: 1:20-50; ChIP: 1:20-50; FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. Note=Localizes to both the large, transcriptionally active, somatic macronucleus (MAC) and the small, transcriptionally inert, germ line micronucleus (MIC). |
| Tissue Specificity | Expressed in testicular cells.Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Immunogen | A synthesized peptide: human Histone H3.1 around the acetylation site of K28 |
| Antigen Species | Human |
| Gene Name | H3C1 |
| Gene ID | |
| Protein Name | Histone H3.1 |
| Uniprot ID | |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H3 is deposited into chromatin exclusively through a DNA replication-coupled pathway that can be associated with either DNA duplication or DNA repair synthesis during meiotic homologous recombination. |
| Molecular Weight | Theoretical: 15 kDa. Actual: 17 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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