Integrin alpha 4 beta 7 Protein, Human, Recombinant (His & Avi)

Name: Integrin alpha 4 beta 7 Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-01749
Rating: 4.5 (1 reviews)

(Synonyms: β7, LPAM, ITGA4&ITGB7, Integrin alpha 4 β 7, Integrin alpha 4 beta 7, beta7, alpha 4) Copy Product Info

Synonyms: β7, LPAM, ITGA4&ITGB7, Integrin alpha 4 β 7, Integrin alpha 4 beta 7, beta7, alpha 4

Catalog No. TMPK-01749 Copy Product Info

Integrin alpha 4 beta 7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P13612-1(ITGA4)&P26010-1(ITGB7).

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Pack Size	Price	USA Stock	Global Stock
5 µg	$90	7-10 days	7-10 days
10 µg	$138	7-10 days	7-10 days
20 µg	$215	7-10 days	7-10 days
50 µg	$392	7-10 days	7-10 days
100 µg	$619	7-10 days	7-10 days
200 µg	$988	7-10 days	7-10 days
500 µg	$1,830	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human ITGA4&ITGB7, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-ITGA4 Antibody, hFc Tag with the EC50 of 5.0 ng/ml determined by ELISA (QC Test).
Description	Integrin alpha 4 beta 7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P13612-1(ITGA4)&P26010-1(ITGB7).
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	P13612-1(ITGA4)&P26010-1(ITGB7)
Construction	Tyr34-Thr977 (ITGA4) acidic tail and Glu20-His723 (ITGB7) basic tail
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 85% as determined by HPLC
Endotoxin	< 1 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	β7, LPAM, ITGA4&ITGB7, Integrin alpha 4 β 7, Integrin alpha 4 beta 7, beta7, alpha 4
Research Background	Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1.

Chemical Properties

Molecular Weight

112.5 kDa (ITGA4) & 81.3 kDa (ITGB7) (Predicted); 70 kDa, 80 kDa, 100-120 kDa and 130-150 (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Integrin alpha 4 beta 7 Protein, Human, Recombinant (His & Avi) chemical structure | Integrin alpha 4 beta 7 Protein, Human, Recombinant (His & Avi) molecular weight