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Anti-ELMO1 Antibody (2W365)
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Catalog No. TMAB-05539 Copy Product Info
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Anti-ELMO1 Antibody (2W365) is a Rabbit antibody targeting ELMO1. Anti-ELMO1 Antibody (2W365) can be used in WB,IP.
Anti-ELMO1 Antibody
(2W365)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 µL | $151 | 7-10 days | 7-10 days | |
| 50 µL | $261 | 7-10 days | 7-10 days | |
| 100 µL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ELMO1 Antibody (2W365) is a Rabbit antibody targeting ELMO1. Anti-ELMO1 Antibody (2W365) can be used in WB,IP. |
| Ig Type | IgG |
| Clone | 2W365 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with ELMO1 monoclonal antibody, unconjugated (TMAB-05539) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK. |
| Tissue Specificity | Widely expressed, with a higher expression in the spleen and placenta. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. |
| Immunogen | A synthesized peptide: human ELMO1 |
| Antigen Species | Human |
| Gene Name | ELMO1 |
| Gene ID | |
| Protein Name | Engulfment and cell motility protein 1 |
| Uniprot ID | |
| Function | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. |
| Molecular Weight | Theoretical: 84 kDa. Actual: 78 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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