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Anti-ELMO1 Antibody (2W365)

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Catalog No. TMAB-05539

Anti-ELMO1 Antibody (2W365) is a Rabbit antibody targeting ELMO1. Anti-ELMO1 Antibody (2W365) can be used in WB,IP.

Anti-ELMO1 Antibody (2W365)

Anti-ELMO1 Antibody (2W365)

😃Good
Catalog No. TMAB-05539
Anti-ELMO1 Antibody (2W365) is a Rabbit antibody targeting ELMO1. Anti-ELMO1 Antibody (2W365) can be used in WB,IP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ELMO1 Antibody (2W365) is a Rabbit antibody targeting ELMO1. Anti-ELMO1 Antibody (2W365) can be used in WB,IP.
Ig Type
IgG
Clone
2W365
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Tissue SpecificityWidely expressed, with a higher expression in the spleen and placenta.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundInvolved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Antigen Details
Immunogen
A synthesized peptide: human ELMO1
Antigen Species
Human
Gene Name
ELMO1
Gene ID
Protein Name
Engulfment and cell motility protein 1
Uniprot ID
Function
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Chemical Properties
Molecular WeightTheoretical: 84 kDa. Actual: 84 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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