IL-31RA Protein, Cynomolgus, Recombinant (His)

Name: IL-31RA Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01744
Rating: 4.5 (1 reviews)

(Synonyms: ZcytoR17, IL-31R-alpha, IL-31RA, GPL, Gp130-like receptor, GLM-R, CRL3Glmr, CRL3) Copy Product Info

Synonyms: ZcytoR17, IL-31R-alpha, IL-31RA, GPL, Gp130-like receptor, GLM-R, CRL3Glmr, CRL3

Catalog No. TMPK-01744 Copy Product Info

IL-31RA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045249656.2.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$147	7-10 days	7-10 days
20 µg	$228	7-10 days	7-10 days
50 µg	$419	7-10 days	7-10 days
100 µg	$665	7-10 days	7-10 days
200 µg	$1,050	7-10 days	7-10 days
500 µg	$1,960	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	Immobilized Cynomolgus IL-31RA, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3 ng/ml determined by ELISA (QC Test). Cynomolgus IL-31, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-31 RA, His Tag with an affinity constant of 6.83 nM as determined in SPR assay (Biacore T200).
Description	IL-31RA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045249656.2.
Species	Cynomolgus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	XP_045249656.2
Construction	Ala20-Glu519
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 85% as determined by HPLC
Endotoxin	< 1 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Synonyms	ZcytoR17, IL-31R-alpha, IL-31RA, GPL, Gp130-like receptor, GLM-R, CRL3Glmr, CRL3
Research Background	Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMR beta). OSMR beta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs). IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.

Chemical Properties

Molecular Weight

58.67 kDa (Predicted); 90-120 kDa (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.