Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-KRT8/18 Antibody (6E645)

😃Good
Catalog No. TMAC-01097

Anti-KRT8/18 Antibody (6E645) is a Rabbit antibody targeting KRT8/18. Anti-KRT8/18 Antibody (6E645) can be used in WB,ICC/IF,IHC,IP,FCM.

Anti-KRT8/18 Antibody (6E645)

Anti-KRT8/18 Antibody (6E645)

😃Good
Catalog No. TMAC-01097
Anti-KRT8/18 Antibody (6E645) is a Rabbit antibody targeting KRT8/18. Anti-KRT8/18 Antibody (6E645) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4987-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-KRT8/18 Antibody (6E645) is a Rabbit antibody targeting KRT8/18. Anti-KRT8/18 Antibody (6E645) can be used in WB,ICC/IF,IHC,IP,FCM.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. They have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratin 8 expression is seen in epithelium and epithelium-derived tumors. The Cytokeratin 8 and 18 pair are normally expressed in simple epithelia, but not in stratified epithelial cells. Research indicates that squamous cell carcinomas derived from stratified epithelia show abnormal expression of Cytokeratin 8 and 18, although it is not known whether these proteins contribute to the malignant phenotype of the cells. Expression of Cytokeratin 8 and 18 in oral squamous cell carcinomas is an independent prognostic marker that indicates a poor prognosis. Cytokeratin 8 expression correlates with malignancy in leukoplakia and carcinomas of the head and neck; it is expressed in all non-small-cell lung cancers. Cytokeratin 8 has been shown to possess extracellular epitopes on tumor cells, which may represent valuable targets for therapy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-KRT8/18 Antibody (6E645) | purchase Anti-KRT8/18 Antibody (6E645) | Anti-KRT8/18 Antibody (6E645) cost | order Anti-KRT8/18 Antibody (6E645) | Anti-KRT8/18 Antibody (6E645) molecular weight