PAI-1 Protein, Human, Recombinant (His) V2

Name: PAI-1 Protein, Human, Recombinant (His) V2
Brand: TargetMol
SKU: TMPY-01474U
Rating: 4.5 (1 reviews)

(Synonyms: SERPINE1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, PLANH1, PAI-1, PAI1, PAI) Copy Product Info

Synonyms: SERPINE1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, PLANH1, PAI-1, PAI1, PAI

Catalog No. TMPY-01474U Copy Product Info

PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$118	7-10 days	7-10 days
20 µg	$196	7-10 days	7-10 days
50 µg	$386	7-10 days	7-10 days
100 µg	$620	7-10 days	7-10 days
200 µg	$995	7-10 days	7-10 days
500 µg	$1,860	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The IC50 value is < 35 nM. (QC Test)
Description	PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P05121-1
Construction	Val24-Pro402
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 50 mM NaAC, 0.1M NaCl, 100mM L-arginine (pH 5.5).
Synonyms	SERPINE1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, PLANH1, PAI-1, PAI1, PAI
Research Background	PAI-1 (plasminogen activator inhibitor-1) is a member of plasminogen cascade with an inhibitory role in plasmin activation. PAI-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic protein are elevated in diabetes and insulin resistant states.

Chemical Properties

Molecular Weight

43.86 kDa (Predicted); 45-55 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.