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PAI-1 Protein, Human, Recombinant (His) V2

Catalog No. TMPY-01474U

PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.

PAI-1 Protein, Human, Recombinant (His) V2

PAI-1 Protein, Human, Recombinant (His) V2

Catalog No. TMPY-01474U
PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 μg$757-10 days7-10 days
10 μg$1187-10 days7-10 days
20 μg$1967-10 days7-10 days
50 μg$3867-10 days7-10 days
100 μg$6207-10 days7-10 days
200 μg$9957-10 days7-10 days
500 μg$1,8607-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]
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Product Information

Biological Activity
Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The IC50 value is < 35 nM. (QC Test)
Description
PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP05121-1
Synonyms
SERPINE1,serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1,PLANH1,PAI-1,PAI1,PAI
Construction
Val24-Pro402
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight43.86 kDa (Predicted); 45-55 kDa (Due to glycosylation)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 50 mM NaAC, 0.1M NaCl, 100mM L-arginine (pH 5.5).
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
PAI-1 (plasminogen activator inhibitor-1) is a member of plasminogen cascade with an inhibitory role in plasmin activation. PAI-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic protein are elevated in diabetes and insulin resistant states.

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