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Synonyms: UNQ309/PRO352, UNQ-309, UNQ309, UNQ 309, TMPY-02031, PSEC-0249, PSEC0249, PSEC 0249, PRO-352, PRO352, PRO 352, CD276 molecule, CD-276, CD276, CD 276, B7RP-2, B7-H3, B7H3, B7 homolog 3, 4Ig-B7-H3, UNQ309, 4Ig-B7-H3


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $123 | 7-10 days | 7-10 days | |
| 10 µg | $189 | 7-10 days | 7-10 days | |
| 20 µg | $293 | 7-10 days | 7-10 days | |
| 50 µg | $548 | 7-10 days | 7-10 days | |
| 100 µg | $873 | 7-10 days | 7-10 days | |
| 200 µg | $1,390 | 7-10 days | 7-10 days | |
| 500 µg | $2,580 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized FITC-Labeled Human B7-H3 (4Ig), hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-B7-H3 Antibody, hFc Tag with the EC50 of 62.5 ng/ml determined by ELISA. |
| Description | B7-H3 (4Ig)/B7-H3b Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 Cells. The accession number is Q5ZPR3-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc (IgG1) |
| Accession Number | Q5ZPR3-1 |
| Construction | Gly27-Thr461 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | UNQ309/PRO352, UNQ-309, UNQ309, UNQ 309, TMPY-02031, PSEC-0249, PSEC0249, PSEC 0249, PRO-352, PRO352, PRO 352, CD276 molecule, CD-276, CD276, CD 276, B7RP-2, B7-H3, B7H3, B7 homolog 3, 4Ig-B7-H3, UNQ309, 4Ig-B7-H3 |
| Research Background | B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. |
| Molecular Weight | 73.4 kDa (Predicted); 90-110 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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